2019

Bateson, M., et al. Smoking does not accelerate leucocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts. Royal Society Open Science

Bentley, A. R., et al. Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics

Bermingham, M.L., et al. Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD.

Booth, T., et al. Reaction time variability and brain white matter integrity. Neuropsychology

Brett, C. E., et al. Predicting change in quality of life from age 79 to 90 in the Lothian Birth Cohort 1921. Quality of Life Research

Cherrie, M. P. C., et al. Association between activity space exposure to park in childhood and adolescence and cognitive ageing in later life.

Chundru, V.K., et al. Examining the Impact of Imputation Errors on Fine-Mapping Using DNA Methylation QTL as a Model Trait.

Clark, D. W., et al. Associations of autozygosity with a broad range of human phenotypes. Nature Communications

Corley, J., et al. Associations between Dietary Inflammatory Index Scores and Inflammatory Biomarkers among Older Adults in the Lothian Birth Cohort 1936 Study. Journal of Nutrition, Health and Aging

Corley, J., et al. Epigenetic signatures of smoking associate with cognitive function, brain structure, and mental and physical health outcomes in the Lothian Birth Cohort 1936. Translational Psychiatry

Cox, S. R., et al. Sleep and cognitive ageing in the 8th decade of life. Sleep

Cukic, I., et al. Cross-sectional associations between personality traits and device-based measures of step count and sedentary behaviour in older age: the Lothian Birth Cohort 1936. BMC Geriatrics

Deary, I., et al. Brain peak width of skeletonised mean diffusivity (PSMD) and cognitive function in later life. Frontiers in Psychiatry

de Vries, P. S., et al. Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. American Journal of Epidemiology

Fawns-Ritchie, C., et al. Genetic contributions to health literacy.

Halachev, M., et al. Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions. PLOS Genetics

Hamilton, O., et al. An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort. International Journal of Obesity

Hill, W. D., et al. A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. Molecular Psychiatry

Hillary, R., et al. Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936.

Humphreys, C. A., et al. A protocol for precise comparisons of small vessel disease lesions between ex vivo magnetic resonance imaging and histopathology. International Journal of Stroke

Imboden, M., et al. Epigenome-wide association study of lung function level and its change. European Respiratory Journal

Kilpeläinen, T. O., et al. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nature Communications

Kraja, A. T., et al. Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. American Journal of Human Genetics

Lam, M., et al. Pleiotropic meta-analysis of cognition, education, and schizophrenia differentiates roles of early neurodevelopmental and adult synaptic pathways. American Journal of Human Genetics

Law, P., et al. Association analyses identify 31 new risk loci for colorectal cancer susceptibility. Nature Communications

Lee, Y., et al. Epigenome-wide association study of leukocyte telomere length. Aging

Lu, A. T., et al. DNA methylation-based estimator of telomere length. Aging

Lund, J., et al. DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns. Clinical Epigenetics

MacPherson, S. E., et al. Individual differences in cognitive processes underlying Trail Making Test-B performance in old age: the Lothian Birth Cohort 1936. Intelligence

Marioni, R. E., et al. Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

Marini, S., et al. Association of apolipoprotein E with intracerebral hemorrhage risk by race/ethnicity: A meta-analysis. JAMA Neurology

McGrory, S., et al. Retinal microvasculature and cerebral small vessel disease in the Lothian Birth Cohort 1936 and Mild Stroke Study.

McGrory, S., et al. Retinal microvascular features and cognitive change in the Lothian-Birth Cohort 1936. 

Muñoz Maniega, S., et al. Spatial gradient of microstructural changes in normal-appearing white matter in tracts affected by white matter hyperintensities in older age. Frontiers in Neurology

Okely, J. A., and Deary, I. J. Longitudinal associations between loneliness and cognitive ability in the Lothian Birth Cohort 1936. The Journals of Gerontology: Series B

Okely, J., et al. Longitudinal associations between hearing loss and general cognitive ability: The Lothian Birth Cohort 1936. Psychology and Aging

Okely, J., et al. Positive and negative well-being and objectively measured sedentary behavior in older adults: evidence from three cohorts. BMC Geriatrics

Ortiz-Ramon, R., et al. Identification of the presence of ischaemic stroke lesions by means of texture analysis on brain magnetic resonance images.

Palmer, V. J., et al. What do older people do when sitting and why? Implications for decreasing sedentary behavior. The Gerontologist

Parker, N., et al.. Corticosteroids and Regional Variations in Thickness of the Human Cerebral Cortex across the Lifespan. Cerebral Cortex

Prendergast, J. G. D., et al. Linked mutations at adjacent nucleotides have shaped human population differentiation and protein evolution. Genome Biology and Evolution

Robertson, N. A., et al. Age-related clonal haematopoiesis is associated with increased epigenetic age. Current Biology

Satizabal, C. L., et al. Genetic architecture of subcortical brain structures in 38,851 individuals. Nature Genetics

Sikdar, S.,et al. Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking. Epigenomics

Stevenson, A.J., et al. Childhood intelligence attenuates the association between biological ageing and health outcomes in later life. Translational Psychiatry

Veluchamy, A., et al. Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease. Arteriosclerosis, Thrombosis, and Vascular Biology

Zhang, F., et al. OSCA: A tool for omic-data-based complex trait analysis. Genome Biology

Zhang, Q., et al. Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Medicine