2018

Browse articles with Lothian Birth Cohorts data published in 2018, organised in alphabetical order by first author:

Aichele, S., et al. Fluid intelligence predicts change in depressive symptoms in later life: The Lothian Birth Cohort 1936. Psychological Science
 
Alloza, C., et al. Polygenic risk score for schizophrenia and structural brain connectivity in older age: a longitudinal connectome and tractography study. NeuroImage
 
Altschul, D. M., et al. Cognitive function in early and later life is associated with blood glucose in older individuals: analysis of the Lothian Birth Cohort of 1936. Diabetologia
 
Anblagan, D., et al. Coupled changes in hippocampal structure and cognitive ability in later life ability in later life. Brain and Behavior
 
Chastin, S.F.M., et al. Systematic comparative validation of self-report measures of sedentary time against an objective measure of postural sitting (activPAL). Journal of Behavioral Nutrition and Physical Activity
 
Cukic, I., et al. Cognitive ability does not predict objectively measured sedentary behaviour: Evidence from three older cohorts. Psychology and Aging
 
Cole, J. H., et al. Brain age predicts mortality. Molecular Psychiatry
 
Corley, J., et al. Healthy cognitive ageing in the Lothian Birth Cohort studies: Marginal gains not magic bullet. Psychological Medicine
 
Cox, S. R., et al. Brain cortical characteristics of lifetime cognitive ageing. Brain Structure & Function
 
Dall, P. M., et al. Characteristics of a protocol to collect objective physical activity/sedentary behaviour data in a large study: Seniors USP (understanding sedentary patterns). Journal for the Measurement of Physical Behaviour
 
Davies, G., et al. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications
 
Fawns-Ritchie, C., et al. Role of cognitive ability in the association between functional health literacy and mortality in the Lothian Birth Cohort 1936: a prospective cohort study. BMJ Open
 
Feitosa, M. F., et al. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PloS One
 
Franceschini, N., et al. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nature Communications
 
Gale, C. R., et al.  Attitudes to ageing and objectively-measured sedentary and walking behaviour in older people: The Lothian Birth Cohort 1936. PloS One
 
Gale, C. R., et al. The epigenetic clock and objectively measured sedentary and walking behavior in older adults: the Lothian Birth Cohort 1936. Clinical Epigenetics
 
Lewis, G. J., et al. Widespread associations between trait conscientiousness and thickness of brain cortical regions. NeuroImage
 
Ligthart, S., et al. Genome analyses of >200,000 individuals identify 58 loci for chromic inflammation and highlight pathways that link inflammation and complex disorders. American Journal of Human Genetics
 
Lu, A., et al. GWAS of epigenetic ageing rates in blood reveals a critical role for TERT. Nature Communications
 
Marioni, R. E., et al. Meta-analysis of epigenome-wide association studies of cognitive abilities. Molecular Psychiatry
 
McCartney, D. L., et al. Epigenetic prediction of complex traits and death. Genome Biology
 
McGrory, S., et al. Towards Standardization of Quantitative Retinal Vascular Parameters: Comparison of SIVA and VAMPIRE Measurements in the Lothian Birth Cohort 1936. Translational Vision Science & Technology
 
McRae, A. F., et al. Identification of 55,000 Replicated DNA Methylation QTL. Scientific Reports
 
Palmer, V., et al. What do older people do when sitting and why?: Implications for decreasing sedentary behaviour. The Gerontologist
 
Pinter, D., et al. Predictors of gait speed and its change over three years in community-dwelling older people. Aging.
 
Qi, T., et al.  Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. Nature Communications
 
Savage, J. E., et al. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics
 
Sibbett, R. A., et al. Does incipient dementia explain normal cognitive decline determinants? Lothian birth cohort 1921. Psychology and Aging
 
Svane, A. M., et al. DNA methylation and all-cause mortality in middle-ages and elderly Danish twins. Genes
 
Taylor, A., Pattie, A., & Deary, I. J. Cohort Profile Update: The Lothian Birth Cohorts of 1921 and 1936. International Journal of Epidemiology
 
Teumer, A., et al. Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Nature Communications
 
Teng, S., et al. Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia. Molecular Psychiatry
 
Turcot, V., et al. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. 
Nature Genetics
 
Wang, Y., et al. Epigenetic influences on aging: A longitudinal genome-wide methylation study in old Swedish twins. Epigenetics
 
Wiseman, S. J., et al. Cognitive abilities, brain white matter hyperintensity volume, and structural network connectivity in older age. Human Brain Mapping
 
Wu, Y. et al. Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits. Nature Communications
 
Zhang, Q., et al.  Genotype effects contribute to variation in longitudinal methylome patterns in older people. Genome Medicine

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